We applied this procedure to a large outbreak of hepatitis C virus caused by a single source and the results obtained played a key role in the trial that led to the conviction of the suspected source. Occasionally, these analyses have been used in courts to provide evidence in cases in which the ascertainment of the source of an outbreak would lead to economic compensation being paid to the infected victims .
Hcv dating Free contact sex hookup
- datingexplored com
- Free porn site chats no sign up
- Free asiancamsex
- Skype sex chat contacts uk
- validating schema java
- Local webcams livexxx
- Men free live chat line sex toronto
The virus spreads primarily by blood-to-blood contact.
The main routes of transmission are intravenous drug use, unscreened blood transfusions (in the developing world) and other incorrect medical procedures, especially those that involve reuse of needles and syringes .
In February 1998, a series of HCV infection cases were detected among patients who had undergone minor surgery at a private hospital in the city of Valencia, Spain.
Molecular phylogenetic analyses are used increasingly in the epidemiological investigation of outbreaks and transmission cases involving rapidly evolving RNA viruses.
Here, we present the results of such an analysis that contributed to the conviction of an anesthetist as being responsible for the infection of 275 of his patients with hepatitis C virus.
We obtained sequences of the NS5B and E1-E2 regions in the viral genome for 322 patients suspected to have been infected by the doctor, and for 44 local, unrelated controls.
The analysis of 4,184 cloned sequences of the E1-E2 region allowed us to exclude 47 patients from the outbreak. We used these data to calibrate a relaxed molecular clock and to determine a rough estimate of the time of infection for each patient.
A similar analysis led to an estimate for the time of infection of the source.
The date turned out to be 10 years before the detection of the outbreak.